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Modern refinements to the drugs have resulted in chemicals like semaglutide and tirzepatide, which are the current most popular GLP-1s for their balance of efficacy and relatively tolerable side effect profiles

What it does is reduce local inflammation, support the maintenance of remaining tissue, and in some cases improve synovial health in a way that changes the pain experience meaningfully

[DOI] [PMC free article] [PubMed] [Google Scholar] 193.Liu Q, Sundar K, Mishra PK, Mousavi G, Liu Z, Gaydo A, Alem F, Lagunoff D, Bleich D, Gause WC

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