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To further explore changes between long-chain hydroxylated and non-hydroxylated SHexCers, we examined heat maps of z -scores in the GPi and GPe brain regions (Supplementary Fig

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Best published PK (Awosemo et al., 2021, rats): ~38% oral bioavailability, ~6 to 7 hr oral half-life

doi:10.1007/s40268-015-0119-3 Caudal route: This is a general approach is simple to administer, but medication doesnt go directly to the source of the pain in the epidural space and around the nerves