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L-theanine ameliorated 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced erythema, increased vascular permeability, epidermal and dermal hyperplasia, and neutrophil infiltration via decreasing platelet endothelial cell adhesion molecule (PECAM)-1 expression and the production of pro-inflammatory cytokines including IL-1, tumor necrosis factor (TNF)- and cyclooxygenase (COX)-2 [34]

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when the nuclear glutathione level is high, the expression of this proliferative marker was also high, while the depletion of nuclear glutathione with DEM caused the important decrease in the level of this protein, and consequently, the decrease in the proliferation