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Carnitine, functioning in the mitochondrial fatty acid oxidation, also plays an important role in regulating the ratio of free coenzyme A (CoA) to acyl-CoA and in the removal of excessive acyl groups (11)

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine

Nevertheless, its reported bioactivities include pathogen and necrotic cell opsonization possibly through their binding to complement factor H-related protein 4, the activation of the classical complement pathway and he regulation of the alternative pathway via their binding to factor H, the inhibition of Membrane Attack Complex (MAC) formation, the stimulation of leukocyte phagocytosis and oxidative metabolism, and also the neutralization of PAF-induced neutrophil degranulation and ROS production possibly via altering actin polymerization by elevating F-actin and reducing G-actin [76,113]