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353 These findings confirm that in the synovium, GLP-1R is expressed on two different cell types, macrophages and fibroblast-like synoviocytes, which are specialized cells distributed within the synovial intima and subintima, and these cell types play important roles in hyaluronic acid synthesis, metabolite processing, and clearance of matrix degradation fragments

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At physiological pH, lysine instead interacts with cellular receptors, allowing the peptide to function as a bridge between copper delivery and cellular signaling

Under cystine-restricted conditions, SCD erythroblasts showed significantly increased ROS and ferroptosis signals by 2,7-dichlorofluorescein (DCF) and Bodipy-C11 staining (Fig

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