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Nepal, M., Mohamed, M.F., Blade, R., Eldesouky, H.E., N, A.T., Seleem, M.N., et al., ACS Infect
In summary, ferroptosis can be triggered by blocking system x c - with exogenous small molecules, interfering with GPX4, disrupting lipid metabolism balance, and iron homeostasis
The significance of differences in protein abundance was determined with a Paired T-test for sibling cohort comparisons and a T-test for comparisons of unrelated groups such as Stage 1 versus Stage 3
This AMPK-mediated inhibition of the TGF-1/Smad signaling pathway is reversed by the AMPK inhibitor Compound C in hepatocyte models, confirming the central role of this pathway (66)
