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2.2 The dynamics of renal injury The renal response to injury is dynamic, and the kidney adapts to maintain homeostasis during the cascade of repair and recovery that follows the primary insult (Bach, 1989)

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The vaccine has been used in infants for more than 40 years and is considered both safe and highly effective at preventing chronic hepatitis B infection in young children, a condition that carries a high risk of liver disease and premature death

We understand the caution expressed by the reviewer to be based on the review by Serras-Millas quoting work by Tamura and colleagues (Thrombosis Research 128, 55-61, 2011)

doi: 10.1159/000051092