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At confluence, CHO-mCD38 cells were co-incubated in culture medium with Ab68 or Ab69 (31.25 nM) in 96 well plates for 24 h

These projections assume consistent daily dosing at 300-500 mcg subcutaneous, caloric deficit of 300-500 calories per day, and regular physical activity

Both routes can effectively raise serum B12 levels in many individuals, as high-dose oral B12 (1000-2000 micrograms) can be absorbed by passive diffusion even without intrinsic factor