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(3) L.S
But there is a grey/intermediary zone that exists (148-500 pmol/L ish), where patients may be deficient on a cellular level (in energy cycle and methylation) and wildly symptomatic including overt bilateral neurological symptoms, cognitive symptoms, severe fatigue (usually in the absence of anaemia) etc
Huang C, Huang L, Wang Y, et al
It has also been reported that sex steroids influence not only growth hormone secretion but also the local synthesis of insulin-like growth factor-I in target tissues and the expression of the growth hormone receptor in various other tissues (4)
Feb 1990;42(2):113-9
