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Although the intrauterine environment was traditionally considered sterile, recent studies have challenged this view, suggesting that microbial DNA may be detected in placental tissues, amniotic fluid, or meconium [47,92,93]

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However, unlike glycolytic and lipogenic pathways, where specific metabolic enzymes such as hexokinase 2 and FAS are known to be deregulated by oncogene(s) or by inactivation of tumor suppressors 16,17 , there is limited evidence for cancer-associated abnormal expression or activity of the enzymes directly involved in the FAO pathway

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