ghk-cu declines with age for Anti-Aging: Does This Copper Peptide Really Work? Middle-aged mice treated with GHK-Cu

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Recovery 12 weeks to months

FOXO4-DRI Key Research Facts Full name: FOXO4 D-Retro-Inverso peptide (FOXO4-DRI) Classification: Cell-penetrating senolytic peptide FOXO4/p53 protein-protein interaction inhibitor Design: D-retro-inverso isoform of FOXO4s p53-binding domain reversed sequence with all D-amino acids Binding target: p53 transactivation domain 2 (TAD2) displaces FOXO4 from the FOXO4-p53 complex Mechanism: FOXO4-DRI binds p53 TAD2 p53 nuclear exclusion p53 mitochondrial translocation BAX activation caspase-3 cleavage senescent cell-selective apoptosis Selectivity basis: FOXO4 is upregulated in senescent cells but expressed at low levels in most non-senescent adult cells selectivity is mechanistically conferred D-amino acid advantage: Proteolytic stability resistant to intracellular peptidases that would rapidly degrade equivalent L-amino acid sequences Structural characterisation: NMR structural models of FOXO4-DRI/p53TAD2 complex resolved (Nature Communications, 2025) confirms disordered-to-ordered transition upon binding Research cell types studied: IMR90 fibroblasts, TM3 Leydig cells, endothelial cells, chondrocytes, keloid fibroblasts, HCT116 cancer cells In vitro working concentration: 25 M used in multiple published studies for senescent cell apoptosis induction What Does FOXO4-DRI Do in Research

Business Type Exporter, Supplier, Trading Company Payment Mode Online Payments (NEFT/RTGS/IMPS), Cheque/DD, Cash Related Products Explore Related Categories More Products From This Seller Seller Details Altair 1, Purmerend, Noord-Holland, 1443, Netherlands The Compare With Similar Products Minimum Order Quantity 50 Vial/Vials 100 Piece/Pieces 10 Vial/Vials Life Span 24 months from date of manufacture 24 months from date of manufacture Pacakaging (Quantity Per Box) 1 vial per box 1 Vial / Box Dosage Form Injection Injection Lyophilized Powder for Injection Indication Soft tissue injury, muscle recovery, inflammation management Tissue regeneration, injury recovery, muscle and tendon healing Salt Composition BPC-157 Acetate Urofollitropin BPC 157 Drug Type Other, Peptide Injection Other, Peptide Therapeutic Ingredients BPC-157 (Pentadecapeptide) Acetate BPC 157 (Body Protective Compound-157) Function Other, Promotes tissue repair and healing, reduces inflammation Other, Musculoskeletal Healing, Tissue & Tendon Repair Recommended For Peptide Therapy, Tissue Repair, Anti-Inflammatory Support Adults Dosage As directed by healthcare professional 75 IU As prescribed by healthcare professional, commonly 2mg per vial Dosage Guidelines Inject subcutaneously or intramuscularly as advised Prescription For subcutaneous or intramuscular use only, as directed by physician Suitable For Adults Other, Men, Women, Aged Person Storage Instructions Store in a cool and dry place, protected from light, refrigerate after opening Cool & Dry Place Store in a cool and dry place, protect from light Payment Terms Cash in Advance (CID) Cash in Advance (CID) Supply Ability 1000 Per Month 5000 Per Month 1000 Per Month Price Or Price Range 290 INR (Approx.) 700 INR (Approx.) People Also Viewed

Originally developed through groundbreaking research at Erasmus University Medical Center, FOXO4-DRI represents a targeted approach to cellular rejuvenation and has shown remarkable promise in preclinical studies for promoting healthspan and addressing age-related cellular dysfunction