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Description
These non-canonical pathways often operate independently of glutathione metabolism, adding layers of complexity to ferroptosis regulation (149)
Some studies have shown an increase in COX levels (Hirai et al., 2001) while others have evidenced a decrease of this enzyme (Nagy et al., 1999
PubMed DOI Sikiric P, Rucman R, Turkovic B, et al
Key points: Technically speaking, the "glutathione system" is a complex network involving glutathione itself, along with the enzymes glutathione peroxidase and glutathione reductase
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