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Relative telomere length and mitochondrial DNA copy number variation with age: association with plasma folate and vitamin B12. Mitochondrion 51 (2020): 79-87.

Supports healthy metabolism: B12 plays a role in cellular metabolism, helping the body function more efficiently when combined with proper nutrition and lifestyle habits

Detoxification is difficult and not suitable

Even meat-eaters can experience deficiency due to poor absorption, which often relies on a stomach-produced protein called intrinsic factor

Upregulation of FcRn is primarily associated with stimulation via tumor necrosis factor (TNF), while other pathways have been identified in non-human models