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Approximately 5 10 5 cells were plated the day before transfection in 6-well plates and collected 2 mL of fresh growth medium prior to transfection

Thus, -syn functions as a critical link between inflammatory and degenerative processes in PD (Serrano et al., 2020)

Pyroptosis, another mode of cell death, is triggered by inflammatory vesicles and is characterized by the discharge of substantial quantities of proinflammatory cytokines, such as IL-18 and IL-1

The source of increased iron in microglia and macrophages is multifactorial and includes the death and damage to iron-rich oligodendrocytes, vascular damage, and infiltration of peripheral immune cells involved in systemic iron homeostasis [180]

Orchard, P