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Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME), is a complex disorder characterized by extreme fatigue that lasts for at least six months and cannot be fully explained by an underlying medical condition

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It also switches the production of black-brown colored eumelanin towards yellow-red pheomelanin, leading to a lighter skin colour

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Endocrinology and Metabolism Clinics of North America, 41(2), 231247

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Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells

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However, self-reported anxiety symptoms may limit the generalizability of the findings

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