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These findings highlight the imperative for predictive models that evaluate present reproductive status while also forecasting future risks by accounting for both direct environmental influences and heritable epigenetic alterations

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Graphical Abstract 1 Introduction Recurrent pregnancy loss (RPL) is a complex reproductive disorder affecting approximately 1% to 5% of women of reproductive age ( The etiology of RPL is multifactorial and highly complex

177 Additionally, through S6K1, mTORC1 facilitates the phosphorylation and activation of the CAD complex, which is the rate-limiting step in pyrimidine biosynthesis