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In pancreatic cells, proglucagon is cleaved to produce glucagon, glicentin-related pancreatic polypeptide (GRPP), intervening peptide-1 (IP-1), and the major proglucagon fragment (MPGF), constituting GLP-1, IP-2, and GLP-2

doi: 10.1182/blood-2011-02-335216

When studied together, the results suggest a pincer maneuver approach: The GLP-1 helps manage the input by controlling appetite and caloric intake

Another major piece of the chronic illness puzzle is the NO/ONOO- (Nitric Oxide/Peroxynitrite) cycle, a mechanism heavily researched in the context of ME/CFS and post-viral fatigue

Neuroprotective Properties : Exhibits protective effects on neurons, potentially aiding cognitive function and mental clarity