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Further studies are necessary to elucidate the role of AGC1 in cancers such as pancreatic, ovarian, lung, and bone malignancies, particularly regarding its involvement in cancer initiation, progression, and metastasis

This protein plays a crucial role in transporting tetrahydrofolate (FH4) across the blood-brain barrier

Neural Regen Res 16(9):1730 Ramsaransing GS, Fokkema MR, Teelken A, Arutjunyan AV, Koch M, De Keyser J (2006) Plasma homocysteine levels in multiple sclerosis

The general reaction performed by sortases involves using its own brand of the 'catalytic triad': i.e

In this study, we show that the heterogenous response of liver cancer cells to methionine restriction is due to, at least partially, their distinct HNF4 status