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Further, diminished growth factor signaling under these conditions significantly attenuates cellular proliferation (154)
A mechanism for glutamate removal
Clinical trials show 4060% symptom reduction, not 100% elimination
By contrast, mature DCs, M1 macrophages and natural killer cells can directly inhibit tumor growth or enhance susceptibility to OC-targeted therapies (99)
For example, EA was conjugated to 2-amino-2-deoxy-d-glucose (EAG) 90 , obtaining an adduct with significant anticancer activity such as EA but without the undesired diuretic activity 90
