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Notably, the low dose of 1D228 at 2 mg/kg already achieved same inhibition rate of Tepotinib at 8 mg/kg (TGI, 1D228-2mg/kg/d:74.4%
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10.1016/j.cogsc.2020.100438 51 GalkinM
Certain ligand-modified nanoparticles have dual targeting capabilities, allowing them to both traverse the BBB and specifically target brain lesion sites
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