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NAC also demonstrates immunomodulatory activity

It can be dynamically regulated, enabling an adjustment in ATP synthesis rate to meet ATP demand [10]

Figure 4 3.5 The damage of antioxidant enzymes is related to M2 macrophage polarization Real-time quantitative PCR showed that IL-4 promoted M2 macrophage polarization by increasing the mRNA expression of CCL24 and MRC1 ( Figure 5A )

Clinical, Cosmetic and Investigational Dermatology 2014:7 submit your manuscript | www.dovepress.com Dovepress Dovepress Dovepress 274 Watanabe et al All authors contributed toward data analysis, drafting and revising the paper and agree to be accountable for all aspects of the work

2010 doi: 10.1128/MCB.01344-09