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Lancet Neurol 14(2):162173 Nagashima M, Ooshiro M, Moriyama A, Sugishita Y, Kadoya K, Sato A, Kitahara T, Takagi R, Urita T, Yoshida Y, Tanaka H, Oshiro T, Okazumi S, Katoh R (2014) Efficacy and tolerability of controlled-release oxycodone for oxaliplatin-induced peripheral neuropathy and the extension of FOLFOX therapy in advanced colorectal cancer patients
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13 MELANOSIS Diagnosis Dark (usually black) flat, smooth, 5- to 25-mm patch Asymmetric or angular configuration Located primarily on nonkeratinizing (mucosal) tissue Unchanging appearance (if patient has previously been aware of the lesion) Incisional biopsy to rule out dysplasia and malignancy Dermoscopy of lentiginosis requires an experienced dermoscopist, and there is no one pattern

It Stays on your SKIN evenly and preventing fading out
