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Bulg J Agric Sci 2015;21:1086-91

Key Takeaway: Glutathione is the body's primary internal antioxidant, but its effectiveness as a supplement depends heavily on how well it can survive the digestive process

Taken together, the above discussion is consistent with the notion that although further studies are needed to better understand the cross talk between OS and tau phosphorylation/dephosphorylation, a close interplay exists that suggests that these events are key components of a vicious circle that plays a crucial role in tau pathology in AD

Among these, the SurE cyclase, a key enzyme in the surugamide biosynthetic pathway from various Streptomyces species, is of particular interest due to its remarkable substrate tolerance, making it a promising candidate for biocatalytic applications