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Description
In brief, when TrkB and p75 NTR co-express in the same cells, p75 NTR enhances neurotrophin binding to TrkB, augmenting both ligand affinity and selectivity, hence, reinforcing the TrkB-mediated trophic response via up-regulation of PI3K/Akt and/or IRAK/NF-B signaling 3

, Ty Beal, PhD , Laurence Chandler , Cindy Davis , John Erdman , Stephen Kritchevsky , Moonseong Heo , Ted Kyle , Caroline Apovian , Ana Reisdorf, MS, RD , Wendy Chung .

A.BellT

The nickname references the Marvel character known for rapid regeneration
It plays a key role in several physiologic and pathologic processes (Ramjiawan et al., 2017
