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Therefore, the present review aims to systematically dissect the core molecular mechanisms of ferroptosis, elucidate its specific pathogenic roles in cognitive disorders including AD, PD and DACI as well as provide a comprehensive overview of emerging diagnostic biomarkers and therapeutic strategies targeting this cell death pathway

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In this context, the onset of AA is characterized by lymphocytic accumulation, while the IFN-mediated positive feedback loop is thought to contribute to the chronicity and progression of the disease (Fig