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[DOI] [PMC free article] [PubMed] 27.Tragni E, Vigna L, Ruscica M, Macchi C, Casula M, Santelia A, et al

Another study published in the Journal of the American Geriatrics Society found that B12 supplements improved memory and cognitive function in older adults with mild cognitive impairment

Some of the most common bacteria that produce B12 are: Aerobic: Pseudomonas dentrificans, Rhodobacter capusulatus, Rhodobacter sphaeroides, Sinorhizobium meliloti

In 2003, Burke and co-workers synthesized 4-(2-aminoethyl)amino-1,8-dimethylimidazo(1,2- a )quinoxaline (BMS-345541, 81 , Figure 19 ) that was a selective IKK inhibitor (IKK IC 50 /IKK IC 50 = 13.3) via binding to the allosteric site of IKK [35]