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Description
Of the cases with induced nephrotoxicity presented in the literature, by far the most common renal lesion is TMA, which is characterized by profound endothelial swelling known as endotheliosis and may be associated with both nephrotic and subnephrotic levels of proteinuria (for review see [18, 30, 53, 6872])

[DOI] [PMC free article] [PubMed] [Google Scholar] 298.Victorelli, S

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Also, this kind of oxygen species is considered the most stable one which can penetrate the cell membrane and damage the cell proteins

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