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When your levels are low, you may have trouble getting and keeping gains, which leads to a lower metabolic rate (16)

Oxidative stress is linked to age-related conditions including cancer, high blood pressure, diabetes, and more

5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."

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Diagnosis typically involves blood tests including full blood count (showing macrocytosis), anti-intrinsic factor antibodies (which are specific for pernicious anaemia), and sometimes anti-parietal cell antibodies