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Post-shortage, the FDA enforced restrictions on compounding, halting most sales by May 2025 and issuing warnings against unapproved GLP-1 drugs falsely marketed for weight loss, citing risks of adverse events from non-FDA-approved formulations

Unlike hepatic insulin resistance, which primarily alters glucose production, peripheral resistance limits systemic glucose disposal, contributing to hyperglycemia, particularly in type 2 diabetes[32,34,36]

Am J Reprod Immunol 91(4):e13847