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2021 May 26;16(5):e0251578

Furthermore, the cell membrane-coated ZIF-8@MnOx nano-platform mPDZM simultaneously loaded with doxorubicin and piperlongumine can effectively promote CD8 + T cell and NK cells infiltration by regulating SASP release, inducing ICD and activating the STING signaling pathway, while reducing Tregs and M2-like macrophages and can further enhance anti-tumor immunity and produce a strong abscopal effect on distant tumors when combinated with anti-PD-L1 therapy (235)
2019 Jan 8;8(1):e009871

Seed dispersal Plants make seeds that can grow into new plants, but if the seeds just fall to the ground under the parent plant, they might not get enough sun, water or nutrients from the soil
