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Description
Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration

doi: 10.1371/journal.pone.0247237 20

ISBN 978-1-4511-5348-4

Cheng Y

WeiJJGuoRJFuGJLiangXXuZMLiaoXet alRegistration of intervention trials of traditional chinese medicine for four neurological diseases on chinese clinical trial registry and clinicaltrials.gov: a narrative review
