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A vitamin B12 deficiency confirmed by laboratory diagnosis can occur in the event of

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It is well known that the onset of ferroptosis requires elevated levels of ferrous ions, which induce lipid peroxidation and ultimately result in cell death

The combined depletion of GPX4 and the inducer of ferroptosis, PUFAPL, works synergistically to decrease the susceptibility of cancer cells to ferroptosis

Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo
