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Clin Cancer Res (2006) 12(15):45628

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Since the microbiome contributes to systemic immunity and can metabolise certain drugs, this may represent an indirect mechanism affecting both host susceptibility to TB and the bioavailability of orally administered anti-TB agents (Leite et al., 2022

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Furthermore, the high prevalence (57%) of persistent VCD six to 12 months after the initial diagnosis is a cause for concern