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As Th17 cells appear to contribute to nigrostriatal degeneration (206, 207), the beneficial effect of T reg may be due to their ability to inhibit TH17 cells

doi: 10.2471/BLT.20.257758 26 LivakKJSchmittgenTD

Previous studies have demonstrated that the use of RXR partial agonists can reduce eosinophilic airway inflammation, a condition mediated, in part, by the chemoattractant activity of CCL11 60

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Upon cellular stress, characteristic of ASD [158], ROS production and elevated intracellular Ca 2+ concentration trigger mPTP opening leading to mitochondrial membrane permeabilization (MMP) [181], initiating apoptosis and necrosis [269], and regulating the activity of autophagy [270, 271]