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Indeed, estrogens decrease the generation and secretion of A peptide by inhibiting the gene expression of -secretase1, by regulating APP processing on cell membranes, and by modulating -secretase and Notch signaling (253)
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doi: 10.1016/j.archger.2007.03.012
Though more research is needed to determine exactly why magnesium helps prevent aura, one theory suggests that its connected to cortical spreading depression, which is a wave of brain activity that produces the visual changes of aura
pmid:7744219 29
