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Conversely, tumor cells that upregulate GPX4 or maintain high GSH pools can evade ferroptosis, supporting proliferation and resistance to oxidative therapies (42, 43)

doi: 10.1016/j.plaphy.2023.108047 9 AuboeufD

Detoxification enzymes of phase II compete with the activating enzymes of phase I to restrict the generation of electrophiles and catalyze the conversion of these electrophilic molecules to inactivate conjugates, making them more soluble in water and more easily get excreted from the body

10.3390/jmse10020231 107 RamsayJ.KattnigD

(2012) Applying pairwise combinations of amino acid mutations for sorting out highly efficient glucosylation tools for chemo-enzymatic synthesis of bacterial oligosaccharides