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By the physicians of Amanecia Health | Updated April 27, 2026 Last reviewed June 18, 2026 by Ann Czarnik, M.D., FACEP

This was to directly prevent epithelial necrosis that may arise in the stomach from the direct injurious effect of various agents applications, and thereby in other tissues as well [41,42,43,44,45,46,47,48,49,50]

The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue

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