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Frequent high heat exposure may temporarily affect sperm quality in some men

Researchers believe this is due to increased ROS (increased oxidative stress) in the pancreatic beta cells.[ref] Related article : Type 2 Diabetes Genes Fatty liver disease: High homocysteine levels are associated with NAFLD (fatty liver disease, MAFLD)

One possible scenario is the metabolic cofactor NADPH, which is known to be required not only for lipid synthesis but also for the function of antioxidant reductases, such as glutathione reductase (GSR) and thioredoxin reductase (TXNRD) 86

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