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DSIP vs prescription sleep medications Prescription medications like zolpidem (Ambien), eszopiclone (Lunesta), or benzodiazepines work through different mechanisms than DSIP, typically enhancing GABAergic activity more broadly

This is achieved by the phase I enzyme-mediated oxidation or reduction of the toxic substrates, followed by the phase II enzymatic conjugation of the newly added or exposed functional groups to glucuronide, sulfate, or glutathione moieties

Tseng HC, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al

Matthew finds a drugged Joe and knows Theo is in trouble

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