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Additionally, microglia, the brains resident immune cells, exhibit a metabolic flexibility that allows them to shift between oxidative phosphorylation and glycolysis, depending on their activation state, which significantly influences neuroinflammation and synaptic plasticity

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The traditional Chinese medicine compound JianpiHuayu Decoction has been shown to enhance NK cell cytotoxicity by suppressing TREM1/DAPI2 signaling in TAMs, thereby alleviating immunosuppression in the TME and synergizing with PD1 inhibitors in hepatocellular carcinoma [222]

This is pretty much how I managed on the ultra burn