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Subq is more common route to take all injection medication because it's not as uncomfortable and has a smaller needle for the injection

Damage to endothelial cells that form the lining of the inner blood vessel exposes an underlying layer of collagen and cells that express an important pro-coagulation protein called tissue factor

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Several possible explanations include: Cobalt sensitivity : B12 contains cobalt, which may cause allergic or histamine reactions in sensitive individuals