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doi: 10.1007/s00281-024-01017-6

While individual responses to supplementation vary, the targeted ingredients in Ultra B-Complex w/PQQ are clinically associated with improvements in several key areas affected by complex chronic illnesses: Profound Fatigue and Post-Exertional Malaise (PEM): By providing adenosylcobalamin, thiamin, and PQQ, this formula directly supports the electron transport chain and stimulates the creation of new mitochondria, helping to restore cellular ATP production and raise the threshold for exertion-induced crashes

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[DOI] [PubMed] [Google Scholar] [25].Cocco T, Sgobbo P, Clemente M, Lopriore B, Grattagliano I, Di Paola M, Villani G