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For its anti-aging mechanisms, see Hallmarks of Aging and Peptide Interventions

The most significant reaction of mevalonate pathway, which represents the rate-limiting reaction, is catalyzed by 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR

In particular, iron-based nanomaterials, such as iron oxide nanoparticles [12,13,14], amorphous iron nanoparticles [15], and FePt nanoparticles [16, 17] have been widely used to increase cellular iron level and trigger the Fenton reaction for generating ROS and LPO

A.PachecoL.ChiancaF.KomatsuS.ChiovattoC.ZatzM.et al (2024)

doi: 10.1093/plphys/kiac123