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Renal cortical mitochondria generate reactive oxygen and reactive nitrogen species, leading to apoptosis and upregulation of nuclear factor kappa-b (NF-B) and pro-inflammatory cytokines 11

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Heterologous expression of -glutamyl transpeptidase from Bacillus atrophaeus GS-16 and its application in the synthesis of -D-glutamyl-L-tryptophan, a known immunomodulatory peptide

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This test may be covered by OHIP depending on clinical context

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This combination treatment suppresses the expression of fibrogenic markers induced by TGF-1 , showing efficacy in preventing colonic fibrosis

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Plos One 2013;8:e75927

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