is there mutation cause glutathione deficiency Controlling entry into mitochondria: potential roles for SLC25A39 in health and (treatment of) disease Frontiers | Glutathione and mitochondria
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In fact, the presence of the serine is not mandatory for the GSH-conjugation reaction as shown in vitro using poplar GSTFs (Pgeot et al., 2017)

Further, selected compounds were identified and validated using targeted data processing

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Arch Toxicol 2015;89:21120 [DOI] [PubMed] [Google Scholar] 119.Du K, McGill MR, Xie Y, Jaeschke H.Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses

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