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Under mild oxidative stress, induction of GSTP1-1 expression and its redox recycling function afford cellular protection

By its antioxidant properties, vitamin C neutralizes free radicals in the oral cavity, thereby reducing oxidative stress and decreasing the release of inflammatory mediators from gingival tissues (Murererehe et al., 2022)
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demonstrated that HOTAIR binds to UPF1, which promotes the degradation of ACSL4, thereby reducing ferroptosis

A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease
