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doi: 10.1016/j.jconrel.2020.07.044

Moreover, overexpression of specific GSTs can also affect chemoresistance, whereas polymorphisms that decrease GST activity are associated with a high risk of developing cancer [72]

Tlaskalov-Hogenov et al

Theres a sense that if theyre not killing people, we should have them available. There have always been complaints that the FDA is too slow, Zuckerman says, but historically, one of the reasons why lots of countries look to our drug regulatory system and our safety data to say if a drug is safe is because our system works really well