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In the MYCN-amplified neuroblastoma, the iron flux was increased and the growth of cancer cells is highly reliable to the system Xc /Glutathione Axis [153]

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Briefly, after enrichment, FoB were washed and resuspended in mannitol and sucrose-BSA (MAS-B) buffer pH 7.2 (70 mM sucrose, 220 mM Mannitol, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM Hepes, 1 mM EGTA, and 0.4% fatty acid-free BSA), and flux measurements were started

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doi: 10.1007/s11357-023-00970-8