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In mammals, spermatogenesis is primarily regulated by Sertoli cells which play an essential role in supporting and nurturing the survival, proliferation, and differentiation of germ cells [5]

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Then, the dried Orlistat granule is screened and then mixed with L-Carnitine granules and the pharmaceutically acceptable carrier, after this step, as an optional step, this composition is taken to its final pharmaceutical form, preferably a capsule