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Risk factors for anaphylactoid reactions include higher infusion rates, a history of atopy or asthma, and female sex, which has been associated with a slightly increased likelihood of adverse reactions

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If the dose was missed by four days or less, it may usually be taken as soon as possible

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Because the level of acetaminophen at the time of the predetoxification assay may not be a peak value (peak may not be achieved before 4 hours post-ingestion), obtain a second plasma level in order to decide whether or not the full 17-dose detoxification treatment is necessary